BACKGROUND: Atypical fibroxanthoma (AFX) and malignant fibrous histiocytoma (MFH) are tumours of the fibrous tissue. They share similar histopathological characteristics, but they differ significantly in their prognosis. AFX, despite its tendency to recur after incomplete excision, has

BACKGROUND Atypical fibroxanthoma (AFX) is an uncommon superficial fibrohistiocytic tumor. It was originally described as a low‐grade dermal tumor of atypical spindle cells, but this view has changed, and it is generally considered to be a tumor of intermediate malignant potential.

They may look like other skin cancers (other than melanoma) and often appear as pink-red raised areas or bumps that do not heal and may be tender. Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. Atypical fibroxanthoma (AFX) was first described by Helwig as a low-grade sarcoma with a favorable prognosis .

Most atypical fibroxanthomas are benign, provided that strict criteria are used for diagnosis. Atypical fibroxanthomas are uncommon but usually occur on the head and neck of older people. They may look like other skin cancers (other than melanoma) and often appear as pink-red raised areas or bumps that do not heal and may be tender. Atypical Fibroxanthoma - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version. Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. 2013-03-26 Atypical fibroxanthoma (AFX) was first reported by Helwig in the early 1960s .

Atypical fibroxanthoma in a 70 yo M w a friable red papule on the R earlobe. https://dermpathpro.com/spot-diagnosis-1/2021-spot-diagnosis/january-2021/

Since the term was coined in the early 1960s, the disease has been viewed in many ways. For a long time AFX was regarded as a superficial variant of malignant fibrous histiocytoma (MFH).

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2020-10-14 Atypical Fibroxanthoma. Atypical fibroxanthoma is a malignant skin tumor with histologic features similar to those of undifferentiated pleomorphic sarcoma, but lacking its more aggressive behavior.

The vast majority of patients have an excellent prognosis following conservative therapy. Recurrences are infrequent, and metastasis is rare. Atypical fibroxanthoma is a type of skin cancer which is often misdiagnosed as a less serious skin condition. Normally, cells in the body will grow and divide to replace old or damaged cells.
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Atypical fibroxanthomas are uncommon but usually occur on the head and neck of older people. They may look like other skin cancers (other than melanoma) and often appear as pink-red raised areas or bumps that do not heal and may be tender. Atypical Fibroxanthoma - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.

They might locally reoccur with the necessity of re-surgery. … Atypical Fibroxanthoma. Atypical fibroxanthoma is a malignant skin tumor with histologic features similar to those of undifferentiated pleomorphic sarcoma, but lacking its more aggressive behavior. The tumor is composed of pleomorphic cells with hyperchromatic nuclei and abundant cytoplasm, commonly arranged in a spindle c ….
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Despite the high-grade morphologic features, atypical fibroxanthoma is an indolent lesion with excellent prognosis. Local excision usually is curative.

The tumour-like growth should be considered a type of skin cancer but it may behave in a benign fashion. A rare type of atypical fibroxanthoma occurs in younger patients on parts of the body that are not normally overexposed to the sun. 2021-03-20 · Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis.

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No. 6 ATYPICAL FIBROXANTHOMA OF SKIN Fretzin and Helwig 1543 TABLE 1. Age Distribution of 139 Patients* with Atypical Fibroxanthoma, by Site of Lesion Total Head and neck Trunk and limbs No. Per cent No. Per cent No. Per cent Age (yrs.1 2 6 20-39 20 15 6 6 14 46 40-59 31 22 20 19 11 36 60-79 61 44 59 54 2 6 80 and over 25 18 21 2 6

The tumor presents as a single cutaneous nodule which is often ulcerated. Atypical Fibroxanthoma of the skin (AFX) is an uncommon tumor of sun-exposed areas of elderly white men, most commonly on the scalp and ears. This fibro-histiocytic spindle cell neoplasm has a potential to metastasize and behave aggressively.